Discovery of Bacterial Fatty Acid Synthase Inhibitors from a Phoma Species as Antimicrobial Agents Using a New Antisense-Based Strategy-Reference-Cited by-同舟云学术

Discovery of Bacterial Fatty Acid Synthase Inhibitors from a Phoma Species as Antimicrobial Agents Using a New Antisense-Based Strategy

Published:2005-12-20 Issue:3 Volume:69 Page:377-380
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Ondeyka John G.¹,Zink Deborah L.¹,Young Katherine¹,Painter Ronald¹,Kodali Srinivas¹,Galgoci Andrew¹,Collado Javier¹,Tormo Jose Ruben¹,Basilio Angela¹,Vicente Francisca¹,Wang Jun¹,Singh Sheo B.¹

Affiliation:

1. Natural Products Chemistry and Medicinal Chemistry and Human and Animal Infectious Diseases, Merck Research Laboratories, Merck & Co., Inc., Rahway, New Jersey 07065, and CIBE, Merck Sharp & Dohme de Espana, S. A. Josefa Valcárcel, Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np050416w

Reference17 articles.

1. Determination of Selectivity and Efficacy of Fatty Acid Synthesis Inhibitors

2. Lipid biosynthesis as a target for antibacterial agents

3. Broad Spectrum Antimicrobial Biocides Target the FabI Component of Fatty Acid Synthesis

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