In Vitro Intrinsic Clearance-Based Optimization of N3-Phenylpyrazinones as Corticotropin-Releasing Factor-1 (CRF1) Receptor Antagonists
Author:
Affiliation:
1. Neuroscience Discovery Chemistry
2. Neuroscience Discovery Biology
3. Pharmaceutical Candidate Optimization
4. Department of Chemical Synthesis
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm900302q
Reference42 articles.
1. Small Molecule Antagonists of the Corticotropin Releasing Factor (CRF)Receptor: Recent Medicinal Chemistry Developments
2. The corticotropin-releasing factor receptor: a novel target for the treatment of depression and anxiety-related disorders
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