Uncovering the Kinetic Characteristics and Degradation Preference of PROTAC Systems with Advanced Theoretical Analyses-Reference-Cited by-同舟云学术

Uncovering the Kinetic Characteristics and Degradation Preference of PROTAC Systems with Advanced Theoretical Analyses

Published:2023-06-05 Issue:6 Volume:3 Page:1775-1789
ISSN:2691-3704
Container-title:JACS Au
language:en
Short-container-title:JACS Au

Author:

Tang Rongfan¹,Wang Zhe²,Xiang Sutong¹,Wang Lingling¹,Yu Yang¹,Wang Qinghua¹,Deng Qirui¹,Hou Tingjun²^ORCID,Sun Huiyong¹^ORCID

Affiliation:

1. Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, Jiangsu, P. R. China

2. Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, Zhejiang, P. R. China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Young Elite Scientists Sponsorship Program by CPU

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Chemistry (miscellaneous),Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jacsau.3c00195

Reference93 articles.

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4. Targeting the Undruggable Proteome: The Small Molecules of My Dreams

5. Proteolysis targeting chimeras (PROTACs) come of age: entering the third decade of targeted protein degradation

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