Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids-Reference-Cited by-同舟云学术

Variation of Tetrahydrofurans in Thyclotides Enhances Oligonucleotide Binding and Cellular Uptake of Peptide Nucleic Acids

Published:2023-06-29 Issue:7 Volume:3 Page:1952-1964
ISSN:2691-3704
Container-title:JACS Au
language:en
Short-container-title:JACS Au

Author:

Zheng Hongchao¹,Clausse Victor¹,Amarasekara Harsha¹,Mazur Sharlyn J.²^ORCID,Botos Istvan³,Appella Daniel H.¹^ORCID

Affiliation:

1. Synthetic Bioactive Molecules Section, Laboratory of Bioorganic Chemistry (LBC), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, 8 Center Drive, Room 404, Bethesda, Maryland 20892, United States

2. Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, United States

3. Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Chemistry (miscellaneous),Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jacsau.3c00198

Reference63 articles.

1. Antisense oligonucleotides: a new therapeutic principle

2. Conjugates of oligonucleotides and modified oligonucleotides: a review of their synthesis and properties

3. Antisense oligonucleotides: modifications and clinical trials