1. Department of Hospital Pharmacy, University of Toyama, Toyama 930-0194, Japan, Institute of Grassland and Environmental Research, Plas Gogerddan, Aberystwyth, Ceredigion, SY23 3EB, United Kingdom, Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, United Kingdom, and Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa 920-1181, Japan