Effect of C9-Methyl Substitution and C8-C9 Conformational Restriction on Antifolate and Antitumor Activity of Classical 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines-Reference-Cited by-同舟云学术

Effect of C9-Methyl Substitution and C8-C9 Conformational Restriction on Antifolate and Antitumor Activity of Classical 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines

Published:2000-07-07 Issue:16 Volume:43 Page:3125-3133
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gangjee Aleem¹,Zeng Yibin¹,McGuire John J.¹,Kisliuk Roy L.¹

Affiliation:

1. Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, Pennsylvania 15282, Grace Cancer Drug Center, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York 14263, and Department of Biochemistry, Tufts University School of Medicine, Boston, Massachusetts 02111

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000130i

Reference38 articles.

1. The renewed potential for folate antagonists in contemporary cancer chemotherapy

Cited by 44 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mitochondrial and Cytosolic One-Carbon Metabolism Is a Targetable Metabolic Vulnerability in Cisplatin-Resistant Ovarian Cancer;Molecular Cancer Therapeutics;2024-02-20

2. Computational description of quantum chemical calculations and pharmacological studies of the synthesized chalcone derivative: A promising NLO material;Journal of the Indian Chemical Society;2022-09

3. Microwave assisted synthesis of 2,3-dihydro-4H-benzo[4,5]thiazolo[3,2-a]furo[2,3-d] pyrimidin-4-ones by radical addition of 2-hydroxy-4H-benzo[4,5]thiazolo[3,2-a] pyrimidin-4-ones to various conjugated alkenes and dienes mediated Mn(OAc)3;Tetrahedron;2022-06

4. Synthetic strategies for anticancer antifolates;New Strategies Targeting Cancer Metabolism;2022

5. Modifications of Isoalantolactone Leading to Effective Anti-bacterial and Anti-viral Compounds;Letters in Drug Design & Discovery;2021-07