Total Synthesis of Two Novel Subpicomolar Sarco/Endoplasmatic Reticulum Ca2+-ATPase Inhibitors Designed by an Analysis of the Binding Site of Thapsigargin-Reference-Cited by-同舟云学术

Total Synthesis of Two Novel Subpicomolar Sarco/Endoplasmatic Reticulum Ca2+-ATPase Inhibitors Designed by an Analysis of the Binding Site of Thapsigargin

Published:2005-10-04 Issue:22 Volume:48 Page:7005-7011
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Søhoel Helmer¹,Liljefors Tommy¹,Ley Steven V.¹,Oliver Steven F.¹,Antonello Alessandra¹,Smith Martin D¹,Olsen Carl Erik¹,Isaacs John T.¹,Christensen S. Brøgger¹

Affiliation:

1. Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen Ø, Denmark, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, United Kingdom, Department of Natural Sciences, The Royal Veterinary and Agricultural University, Bülowsvej 17, DK-1870 Frederiksberg C, Denmark, and The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland 21231

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm058036v

Reference30 articles.

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