Simple Modifications of the Serpin Reactive Site Loop Convert SCCA2 into a Cysteine Proteinase Inhibitor: A Critical Role for the P3‘ Proline in Facilitating RSL Cleavage-Reference-Cited by-同舟云学术

Simple Modifications of the Serpin Reactive Site Loop Convert SCCA2 into a Cysteine Proteinase Inhibitor: A Critical Role for the P3‘ Proline in Facilitating RSL Cleavage

Published:2000-05-20 Issue:24 Volume:39 Page:7081-7091
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Luke Cliff¹,Schick Charles¹,Tsu Christopher¹,Whisstock James C.¹,Irving James A.¹,Brömme Dieter¹,Juliano Luiz¹,Shi Guo-Ping¹,Chapman Harold A.¹,Silverman Gary A.¹

Affiliation:

1. Department of Pediatrics, Harvard Medical School and Division of Newborn Medicine, Children's Hospital, 300 Longwood Avenue, Boston, Massachusetts 02115, Department of Biochemistry and Molecular Biology, Monash University, Melbourne, Victoria, Australia, Department of Human Genetics, Mount Sinai School of Medicine, Fifth Avenue at 100th Street, New York, New York 10029, Department of Biophysics, Federal University of São Paulo, São Paulo, SP, Brazil 04044, and Department of Medicine, Harvard Medical...

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi000050g

Reference43 articles.

1. Gettins, P. G. W., Patston, P. A., and Olson, S. T. (1996) inMolecular Biology Intelligence Unit, p 202, R. G. Landes Company and Chapman & Hall, Austin, TX.

2. Schick, C., Pemberton, P. A., Shi, G.P., Kamachi, Y., Cataltepe, S., Bartuski, A. J., Gornstein, E. R., Bromme, D., Chapman, H. A., and Silverman, G. A. (1998)Biochemistry37, 5258−5266.

3. Squamous Cell Carcinoma Antigen 2 Is a Novel Serpin That Inhibits the Chymotrypsin-like Proteinases Cathepsin G and Mast Cell Chymase

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