Influence Mechanism of Polymeric Excipients on Drug Crystallization: Experimental Investigation and Chemical Potential Gradient Model Analysis and Prediction-Reference-Cited by-同舟云学术

Influence Mechanism of Polymeric Excipients on Drug Crystallization: Experimental Investigation and Chemical Potential Gradient Model Analysis and Prediction

Published:2023-04-12 Issue:5 Volume:23 Page:3862-3872
ISSN:1528-7483
Container-title:Crystal Growth & Design
language:en
Short-container-title:Crystal Growth & Design

Author:

Chen Qiao¹,Weng Jingyun¹,Sadowski Gabriele²,Ji Yuanhui¹^ORCID

Affiliation:

1. Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, People’s Republic of China

2. Department of Biochemical and Chemical Engineering, Laboratory of Thermodynamic, TU Dortmund, Emil-Figge-Str. 70, D-44227 Dortmund, Germany

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.cgd.3c00314

Reference51 articles.

1. Nanotechnology based approaches to enhance aqueous solubility and bioavailability of griseofulvin: A literature survey

2. Moisture-Induced Amorphous Phase Separation of Amorphous Solid Dispersions: Molecular Mechanism, Microstructure, and Its Impact on Dissolution Performance

3. Physical stability of amorphous pharmaceutical solids: Nucleation, crystal growth, phase separation and effects of the polymers

4. Continuous Plug Flow Crystallization of Pharmaceutical Compounds

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