Five Cocrystal Forms of Antitumor Drug Temozolomide with p-Hydroxybenzoic Acid: Structure, Computational Analysis, Characterizations, Stability, and Transformation

Author:

Yu Hongmei1ORCID,Zhang Baoxi1ORCID,Xing Wenhui1,Liu Meiju1,Yang Dezhi1ORCID,He Guorong2,Wang Fengfeng3,Zhang Li1ORCID,Gong Ningbo1,Lu Yang1ORCID,Du Guanhua2

Affiliation:

1. Beijing Key Laboratory of Polymorphic Drugs, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

2. Beijing City Key Laboratory of Drug Target Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College. Beijing 100050, China

3. National Institutes for Food and Drug Control, Beijing 102629, China

Funder

Government of Shandong Province

Natural Science Foundation of Beijing Municipality

Central University Basic Research Fund of China

Chinese Pharmacopoeia Commission Drug Standard Promoting Fund

Publisher

American Chemical Society (ACS)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

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