Discovery of 5-[5-Fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic Acid (2-Diethylaminoethyl)amide, a Novel Tyrosine Kinase Inhibitor Targeting Vascular Endothelial and Platelet-Derived Growth Factor Receptor Tyrosine Kinase-Reference-Cited by-同舟云学术

Discovery of 5-[5-Fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic Acid (2-Diethylaminoethyl)amide, a Novel Tyrosine Kinase Inhibitor Targeting Vascular Endothelial and Platelet-Derived Growth Factor Receptor Tyrosine Kinase

Published:2003-03-01 Issue:7 Volume:46 Page:1116-1119
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sun Li¹,Liang Chris¹,Shirazian Sheri¹,Zhou Yong¹,Miller Todd¹,Cui Jean¹,Fukuda Juri Y.¹,Chu Ji-Yu¹,Nematalla Asaad¹,Wang Xueyan¹,Chen Hui¹,Sistla Anand¹,Luu Tony C.¹,Tang Flora¹,Wei James¹,Tang Cho¹

Affiliation:

1. SUGEN, Inc., 230 E. Grand Avenue, South San Francisco, California 94080

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0204183

Reference13 articles.

1. Cherrington, J. M.; Strawn, L. M.; Shawver, L. K. New paradigms for the treatment of cancer; the role of anti-angiogenesis agents. InAdvances inCancer Research, 1st ed.; Klein, G., Van de Woude, G. F., Eds. Academic Press: San Diego, CA, 2000; Vol. 70, pp 1−38.

2. VEGF: an update on biological and therapeutic aspects

3. Evidence for Distinct Signaling Properties and Biological Responses Induced by the PDGF Receptor α and β Subtypes

Cited by 509 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. FDA-approved small molecule kinase inhibitors for cancer treatment (2001–2015): Medical indication, structural optimization, and binding mode Part I;Bioorganic & Medicinal Chemistry;2024-09

2. Pyrrole-containing hybrids as potential anticancer agents: An insight into current developments and structure-activity relationships;European Journal of Medicinal Chemistry;2024-07

3. Synthesis and comprehensive characterization with anticancer activity assessment of salicylaldehyde and 2-acetylphenol based chitosan thiosemicarbazones and their copper(II) complexes;Carbohydrate Polymer Technologies and Applications;2024-06

4. Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationships;European Journal of Medicinal Chemistry;2024-05

5. Potentials and future perspectives of multi-target drugs in cancer treatment: the next generation anti-cancer agents;Cell Communication and Signaling;2024-04-15