Rigid 2′,4′-Difluororibonucleosides: Synthesis, Conformational Analysis, and Incorporation into Nascent RNA by HCV Polymerase-Reference-Cited by-同舟云学术

Rigid 2′,4′-Difluororibonucleosides: Synthesis, Conformational Analysis, and Incorporation into Nascent RNA by HCV Polymerase

Published:2014-06-06 Issue:12 Volume:79 Page:5627-5635
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Martínez-Montero Saúl¹,Deleavey Glen F.¹,Kulkarni Anupriya²,Martín-Pintado Nerea³,Lindovska Petra¹,Thomson Michael¹,González Carlos³,Götte Matthias²,Damha Masad J.¹

Affiliation:

1. Department of Chemistry, McGill University, 801 Sherbrooke Street West, Montreal, QC Canada H3A 0B8

2. Department of Microbiology and Immunology, McGill University, 3775 University, Montreal, QC Canada H3A 2B4

3. Instituto de Química Física Rocasolano, CSIC, C/. Serrano 119, 28006 Madrid, Spain

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo500794v

Reference51 articles.

1. Enzymology of Purine and Pyrimidine Antimetabolites Used in the Treatment of Cancer

2. Antiviral drugs in current clinical use

3. Conformational analysis of the sugar ring in nucleosides and nucleotides. New description using the concept of pseudorotation

4. Nucleosides with a Twist. Can Fixed Forms of Sugar Ring Pucker Influence Biological Activity in Nucleosides and Oligonucleotides?

Cited by 47 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Investigating the Effect of Chemical Modifications on the Ribose Sugar Conformation, Watson–Crick Base Pairing, and Intrastrand Stacking Interactions: A Theoretical Approach;The Journal of Physical Chemistry B;2024-08-22

2. Discovery of C-Linked Nucleoside Analogues with Antiviral Activity against SARS-CoV-2;ACS Infectious Diseases;2024-04-23

3. Synthesis and evaluation of NHC derivatives and 4′-fluorouridine prodrugs;Organic & Biomolecular Chemistry;2023

4. 4′-Fluoro-nucleosides and nucleotides: from nucleocidin to an emerging class of therapeutics;Chemical Society Reviews;2023

5. From Oxetane to Thietane: Extending the Antiviral Spectrum of 2′-Spirocyclic Uridines by Substituting Oxygen with Sulfur;ACS MED CHEM LETT;2022