1. Department of Biophysics, Universidade Federal de São Paulo, Rua 3 de Maio 100, CEP 04044-020, São Paulo, SP, Brazil, Department of Biochemistry, Institute of Chemistry, UNESP, CEP 14800-060, Araraquara, SP, Brazil, and Department of Biochemistry, Institute of Chemistry, USP, CEP 05599-970, São Paulo, SP, Brazil