Discovery of High-Affinity Ligands of σ1 Receptor, ERG2, and Emopamil Binding Protein by Pharmacophore Modeling and Virtual Screening-Reference-Cited by-同舟云学术

Discovery of High-Affinity Ligands of σ1 Receptor, ERG2, and Emopamil Binding Protein by Pharmacophore Modeling and Virtual Screening

Published:2005-06-24 Issue:15 Volume:48 Page:4754-4764
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Laggner Christian¹,Schieferer Claudia¹,Fiechtner Birgit¹,Poles Gloria¹,Hoffmann Rémy D.¹,Glossmann Hartmut¹,Langer Thierry¹,Moebius Fabian F.¹

Affiliation:

1. Institute of Pharmacy, Department of Pharmaceutical Chemistry, and Center for Molecular Biosciences (CMBI), University of Innsbruck, Innrain 52, A-6020 Innsbruck, Austria; Department of Biochemical Pharmacology, Innsbruck Medical University, Peter-Mayr-Str. 1, A-6020 Innsbruck, Austria; and Accelrys SARL, Parc Club Orsay Université, 20, rue Jean Rostand, 91898 Orsay Cédéx, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049073%2B

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5. High affinity of sigma1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7isomerase

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