Structural Basis of Ligand Binding to UDP-Galactopyranose Mutase from Mycobacterium tuberculosis Using Substrate and Tetrafluorinated Substrate Analogues

Author:

van Straaten Karin E.1,Kuttiyatveetil Jijin R. A.1,Sevrain Charlotte M.2,Villaume Sydney A.2,Jiménez-Barbero Jesús345,Linclau Bruno6,Vincent Stéphane P.2,Sanders David A. R.1

Affiliation:

1. Department of Chemistry, University of Saskatchewan, 110 Science Place, Saskatoon S7N 5C9, Canada

2. Department of Chemistry, University of Namur, Rue de Bruxelles 61, 5000 Namur, Belgium

3. Department of Chemical and Physical Biology, Centro de Investigaciones Biologicas, CSIC, Ramiro de Maeztu 9, 28040 Madrid, Spain

4. Structural Biology Unit, CIC bioGUNE, Parque Tecnologico de Bizkaia Building 801A, 48160 Derio, Spain

5. IKERBASQUE, Basque Foundation for Science, 48011 Bilbao, Spain

6. Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

University of Southampton

European Commission

Fonds pour la Formation à la Recherche dans l’Industrie et dans l’Agriculture

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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