Coumarin-Based Inhibitors of Human NAD(P)H:Quinone Oxidoreductase-1. Identification, Structure–Activity, Off-Target Effects and In Vitro Human Pancreatic Cancer Toxicity-Reference-Cited by-同舟云学术

Coumarin-Based Inhibitors of Human NAD(P)H:Quinone Oxidoreductase-1. Identification, Structure–Activity, Off-Target Effects and In Vitro Human Pancreatic Cancer Toxicity

Published:2007-11-14 Issue:25 Volume:50 Page:6316-6325
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Nolan Karen A.¹,Zhao He¹,Faulder Paul F.¹,Frenkel A. David¹,Timson David J.¹,Siegel David¹,Ross David¹,Burke Jr. Terrence R.¹,Stratford Ian J.¹,Bryce Richard A.¹

Affiliation:

1. School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, U.K., Laboratory of Medicinal Chemistry, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, School of Biological Sciences, Queen’s University Belfast, Medical Biology Centre, 97 Lisburn Road, Belfast, BT9 7BL, U.K., and Department of Pharmaceutical Sciences and Cancer Center, School of Pharmacy, University of Colorado and Health Sciences Center, Denver, Colorado 80220

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070472p

Reference41 articles.

1. Studies on TPN-linked oxidations

2. Human dioxin-inducible cytosolic NAD(P)H:menadione oxidoreductase. cDNA sequence and localization of gene to chromosome 16.

3. [56] DT diaphorase

4. The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction.

5. Purification and some properties of a highly dicumarol-sensitive liver diaphorase

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