Novel RNA Synthesis Method Using 5‘-O-Silyl-2‘-O-orthoester Protecting Groups
Author:
Affiliation:
1. Dharmacon Research, Inc., Boulder, Colorado 80301 Ribozyme Pharmaceuticals, Inc., Boulder, Colorado 80301 University of Colorado, Boulder, Colorado 80309
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja980730v
Reference24 articles.
1. Tethering Ribozymes to a Retroviral Packaging Signal for Destruction of Viral RNA
2. Exploiting the chemical synthesis of RNA
3. The synthesis of oligoribonucleotides. II. The use of silyl protecting groups in nucleoside and nucleotide chemistry. VII
4. The automated chemical synthesis of long oligoribuncleotides using 2'-O-silylated ribonucleoside 3'-O-phosphoramidites on a controlled-pore glass support: synthesis of a 43-nucleotide sequence similar to the 3'-half molecule of an Escherichia coli formylmethionine tRNA
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