Discovery of MK-3207: A Highly Potent, Orally Bioavailable CGRP Receptor Antagonist-Reference-Cited by-同舟云学术

Discovery of MK-3207: A Highly Potent, Orally Bioavailable CGRP Receptor Antagonist

Published:2010-01-12 Issue:1 Volume:1 Page:24-29
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Bell Ian M.¹²³⁴⁵,Gallicchio Steven N.¹²³⁴⁵,Wood Michael R.¹²³⁴⁵,Quigley Amy G.¹²³⁴⁵,Stump Craig A.¹²³⁴⁵,Zartman C. Blair¹²³⁴⁵,Fay John F.¹²³⁴⁵,Li Chi-Chung¹²³⁴⁵,Lynch Joseph J.¹²³⁴⁵,Moore Eric L.¹²³⁴⁵,Mosser Scott D.¹²³⁴⁵,Prueksaritanont Thomayant¹²³⁴⁵,Regan Christopher P.¹²³⁴⁵,Roller Shane¹²³⁴⁵,Salvatore Christopher A.¹²³⁴⁵,Kane Stefanie A.¹²³⁴⁵,Vacca Joseph P.¹²³⁴⁵,Selnick Harold G.¹²³⁴⁵

Affiliation:

1. Departments of Medicinal Chemistry

2. In Vitro Sciences

3. Clinical PK/PD

4. Central Pharmacology

5. Pain/Migraine

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml900016y