Synthesis and Biological Evaluation of Novel Prodrugs of Anthracyclines for Selective Activation by the Tumor-Associated Protease Plasmin-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of Novel Prodrugs of Anthracyclines for Selective Activation by the Tumor-Associated Protease Plasmin

Published:1999-11-25 Issue:25 Volume:42 Page:5277-5283
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

de Groot Franciscus M. H.¹,de Bart Anton C. W.¹,Verheijen Jan H.¹,Scheeren Hans W.¹

Affiliation:

1. Department of Organic Chemistry, NSR-Center for Molecular Structure, Design and Synthesis, University of Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands, and TNO Prevention and Health, Division of Vascular and Connective Tissue Research, Gaubius Laboratorium, Zernikedreef 9, 2333 CK, Leiden, The Netherlands

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9910472

Reference29 articles.

1. A summary of monoclonal antibody-enzyme/prodrug

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