Synthesis and Evaluation of 3-Aryloxymethyl-1,2-dimethylindole-4,7-diones as Mechanism-Based Inhibitors of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Activity-Reference-Cited by-同舟云学术

Synthesis and Evaluation of 3-Aryloxymethyl-1,2-dimethylindole-4,7-diones as Mechanism-Based Inhibitors of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Activity

Published:2007-10-18 Issue:23 Volume:50 Page:5780-5789
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Colucci Marie A.¹,Reigan Philip¹,Siegel David¹,Chilloux Aurélie¹,Ross David¹,Moody Christopher J.¹

Affiliation:

1. School of Chemistry, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom, and Department of Pharmaceutical Sciences and Cancer Center, School of Pharmacy, University of Colorado at Denver and Health Sciences Center, Denver, Colorado 80262

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070396q

Reference30 articles.

1. [57] Beef heart TPNH-DPN pyridine nucleotide transhydrogenases

2. NAD(P)H:quinone oxidoreductase 1 (NQO1): chemoprotection, bioactivation, gene regulation and genetic polymorphisms

3. Quinone Reductases Multitasking in the Metabolic World

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