Alkyl C−O Ring Cleavage of Bicyclic β-Lactones with Normant Reagents: Synthesis of a Merck IND Intermediate
Author:
Affiliation:
1. Department of Chemistry, Texas A&M University, P.O. Box 30012, College Station, Texas 77842-3012
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol070572p
Reference26 articles.
1. Intramolecular, Nucleophile-Catalyzed Aldol-Lactonization (NCAL) Reactions: Catalytic, Asymmetric Synthesis of Bicyclic β-Lactones
2. Bicyclic β-Lactones via Intramolecular NCAL Reactions with Cinchona Alkaloids: Effect of the C9-Substituent on Enantioselectivity and Catalyst Conformation
3. Bicyclic- and Tricyclic-β-lactones via Organonucleophile-Promoted Bis-Cyclizations of Keto Acids: Enantioselective Synthesis of (+)-Dihydroplakevulin
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