Process Development of a Dual MMP/TNF Inhibitor (SDZ 242-484)
Author:
Affiliation:
1. Process Research and Development, Chemical and Analytical Development, Novartis Pharma AG, CH 4002, Basel, Switzerland
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/op025536e
Reference20 articles.
1. Functional analogs of CC-1065 and the duocarmycins incorporating the 9a-(chloromethyl)-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one (C2BI) alkylation subunit: synthesis and preliminary DNA alkylation studies
2. Selectivity in the amination of allylic alcohols via intramolecular amidomercuration
3. Enantioselective preparation of 3-substituted 4-pentenoic acids via the Claisen rearrangement
4. A new free radical route to oximes using alkyl halides, hexabutylditin and readily available nitrite esters
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