Isolation and Structure Elucidation of Sch 642305, a Novel Bacterial DNA Primase Inhibitor Produced by Penicillium verrucosum-Reference-Cited by-同舟云学术

Isolation and Structure Elucidation of Sch 642305, a Novel Bacterial DNA Primase Inhibitor Produced by Penicillium verrucosum

Published:2003-11-15 Issue:12 Volume:66 Page:1527-1530
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Chu Min¹,Mierzwa Ronald¹,Xu Ling¹,He Ling¹,Terracciano Joseph¹,Patel Mahesh¹,Gullo Vincent¹,Black Todd¹,Zhao Wenjun¹,Chan Tze-Ming¹,McPhail Andrew T.¹

Affiliation:

1. Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033, and P.M. Gross Chemical Laboratory, Department of Chemistry, Duke University, Durham, North Carolina 27708-0346

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np0302302

Reference9 articles.

1. Building Communication Networks: International Network for the Study and Prevention of Emerging Antimicrobial Resistance (INSPEAR)

2. dnaG gene product, a rifampicin-resistant RNA polymerase, initiates the conversion of a single-stranded coliphage DNA to its duplex replicative form.

3. Mutations in the Escherichia coli dnaG gene suggest coupling between DNA replication and chromosome partitioning

4. Purification and characterization of a mutant DnaB protein specifically defective in ATP hydrolysis

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