1. Department of Physics, University of Genoa, via Dodecaneso 33, 16146 Genoa, Italy, Department of Endocrinology and Metabolism, University of Pisa, Via Paradisa 2, 56124 Pisa-Cisanello, Italy, and LAMBS-IFOM, MicroScoBIO Research Center, University of Genoa, via Dodecaneso 33, 16146 Genoa, Italy