Defining the Structural Parameters That Confer Anticonvulsant Activity by the Site-by-Site Modification of (R)-N′-Benzyl 2-Amino-3-methylbutanamide-Reference-Cited by-同舟云学术

Defining the Structural Parameters That Confer Anticonvulsant Activity by the Site-by-Site Modification of (R)-N′-Benzyl 2-Amino-3-methylbutanamide

Published:2011-09-13 Issue:19 Volume:54 Page:6432-6442
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

King Amber M.¹,De Ryck Marc²,Kaminski Rafal²,Valade Anne²,Stables James P.³,Kohn Harold¹⁴

Affiliation:

1. Division of Medicinal Chemistry and Natural Products, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599-7568, United States

2. CNS Research, UCB Pharma S.A., Chemin du Foriest, B-1420 Braine-l’Alleud, Belgium

3. Anticonvulsant Screening Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 6001 Executive Boulevard, Suite 2106, Rockville, Maryland 20892, United States

4. Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200760a

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3. A rational guide to routine blood monitoring in patients receiving antiepileptic drugs

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