Analysis of Pyridyloxobutyl DNA Adducts in F344 Rats Chronically Treated with (R)- and (S)-N‘-Nitrosonornicotine
Author:
Affiliation:
1. Department of Medicinal Chemistry, and The Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx060208j
Reference38 articles.
1. Tobacco carcinogens, their biomarkers and tobacco-induced cancer
2. Wang, L., Spratt, T. E., Liu, X.K., Hecht, S. S., Pegg, A. E., and Peterson, L. A. (1997) Pyridyloxobutyl adductO6-[4-oxo-4-(3-pyridyl)butyl]guanine is present in 4-(acetoxymethylnitrosamino)-1-(3-pyridyl)-1-butanone-treated DNA and is a substrate forO6-alkylhuanine-DNA alkyltransferase.Chem. Res. Toxicol.10, 562−567.
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