Chemical Conjugation of the Neuropeptide Kyotorphin and Ibuprofen Enhances Brain Targeting and Analgesia-Reference-Cited by-同舟云学术

Chemical Conjugation of the Neuropeptide Kyotorphin and Ibuprofen Enhances Brain Targeting and Analgesia

Published:2011-08-24 Issue:5 Volume:8 Page:1929-1940
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Ribeiro Marta M. B.¹,Pinto Antónia R. T.²³,Domingues Marco M.¹,Serrano Isa¹,Heras Montserrat⁴,Bardaji Eduard R.⁴,Tavares Isaura²³,Castanho Miguel A.¹

Affiliation:

1. Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Av. Professor Egas Moniz, 1649-028 Lisboa, Portugal

2. Instituto de Histologia e Embriologia, Faculdade de Medicina do Porto, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal

3. Instituto de Biologia Celular e Molecular, Rua Campo Alegre, 4150-180 Porto, Portugal

4. Laboratori d'Innovació en Processos i Productes de Síntesi Orgànica (LIPPSO), Departament de Química, Universitat de Girona, Campus Montilivi, 17071 Girona, Spain

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp2003016

Reference47 articles.

1. A novel analgesic dipeptide from bovine brain is a possible Met-enkephalin releaser

2. Isolation and identification of an analgesic opioid dipeptide kyotorphin (TYR-ARG) from bovine brain

3. Effects of a number of short peptides isolated from the brain of the hibernating ground squirrel on the eeg and behavior in rats

4. Seizure-protecting effects of kyotorphin and related peptides in an animal model of epilepsy

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