Design and Synthesis of Cannabinoid Receptor 1 Antagonists for Peripheral Selectivity
Author:
Affiliation:
1. Discovery Sciences, Research Triangle Institute, 3040 Cornwallis Road, P.O. Box 12194, Research Triangle Park, North Carolina 27709, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm201731z
Reference23 articles.
1. The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2. Cannabinoid receptor CB1 activates the Na+/H+exchanger NHE-1 isoform via Gi-mediated mitogen activated protein kinase signaling transduction pathways
3. A Selective Inverse Agonist for Central Cannabinoid Receptor Inhibits Mitogen-activated Protein Kinase Activation Stimulated by Insulin or Insulin-like Growth Factor 1
4. Cannabinoid receptor antagonists: pharmacological opportunities, clinical experience, and translational prognosis
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