Rapid Discovery of Potent siRNA-Containing Lipid Nanoparticles Enabled by Controlled Microfluidic Formulation-Reference-Cited by-同舟云学术

Rapid Discovery of Potent siRNA-Containing Lipid Nanoparticles Enabled by Controlled Microfluidic Formulation

Published:2012-04-10 Issue:16 Volume:134 Page:6948-6951
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Chen Delai¹²,Love Kevin T.¹,Chen Yi¹,Eltoukhy Ahmed A.¹,Kastrup Christian¹,Sahay Gaurav¹,Jeon Alvin¹,Dong Yizhou¹,Whitehead Kathryn A.¹,Anderson Daniel G.¹²

Affiliation:

1. David H. Koch Institute for Integrative Cancer Research, Department of Chemical Engineering, and Division of Health Science Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

2. Department of Anesthesiology, Children’s Hospital Boston, 300 Longwood Avenue, Boston, Massachusetts 02115, United States

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja301621z

Reference33 articles.

1. RNAi therapeutics: a potential new class of pharmaceutical drugs

2. Knocking down barriers: advances in siRNA delivery

3. Improved DNA: liposome complexes for increased systemic delivery and gene expression

4. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

5. Lipid-like materials for low-dose, in vivo gene silencing

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