1. CIMAINA and Dipartimento di Fisica, University of Milano, via Celoria 16, 20133 Milano, Italy, SEMM, Scuola Europea di Medicina Molecolare, and Department of Experimental Oncology, European Institute of Oncology, Campus IFOM-IEO, Via Adamello 16, 20139 Milan, Italy, and Tethis srl, via Russoli 3, 20143 Milano, Italy