Total Synthesis of (+)-19-Deoxyicetexone, (−)-Icetexone, and (+)-5-Epi-icetexone

Author:

Majetich George1,Grove Jeremy L.1

Affiliation:

1. Department of Chemistry, University of Georgia, Athens, Georgia, 30602

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference38 articles.

1. Duke, J. A.InA Handbook of Medicinal Herbs;CRC Press:Boca Raton, 1985; pp 118,419−422.

2. Abietane and icetexane diterpenoids from the roots of Salvia aspera

3. 5-Epi-icetexone (3), exhibits a strong antiproliferative effect on the parasiteTrypanosoma cruzi, the causative agent in Chagas’ disease; see:

4. A novel icetexane diterpene, 5-epi-icetexone from Salvia gilliessi is active against Trypanosoma cruzi

5. The Total Snthesis of (±)-barbatusol

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