Identification of 4,5-Dihydro-4-hydroxygeldanamycins As Shunt Products of Geldanamycin Biosynthesis-Reference-Cited by-同舟云学术

Identification of 4,5-Dihydro-4-hydroxygeldanamycins As Shunt Products of Geldanamycin Biosynthesis

Published:2012-07-31 Issue:8 Volume:75 Page:1480-1484
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Li Ting¹,Ni Siyang¹,Jia Changhong¹,Wang Hongyuan¹,Sun Guizhi¹,Wu Linzhuan¹,Gan Maoluo¹,Shan Guangzhi¹,He Weiqing¹,Lin Ling¹,Zhou Hongxia¹,Wang Yiguang¹

Affiliation:

1. Key Laboratory of Biotechnology of Antibiotics of Ministry of Health, Institute of Medicinal Biotechnology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100050, People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np3001738

Reference27 articles.

1. Chrysanthemic acid. V. Thermal and photo [3,3]sigmatropic rearrangements in the cis-2,2-dimethyl-3-isobutenylcyclopropyl isocyanate-3,6-dihydro-3,3,6,6-tetramethyl-2H-azepin-2-one system

2. Carbon-13 as a biosynthetic tool. III. Geldyanamycin biosynthesis and carbon magnetic resonance

3. The description and antibiotic production of Streptomyces hygroscopicus var. geldanus.

4. Crystal Structure of an Hsp90–Geldanamycin Complex: Targeting of a Protein Chaperone by an Antitumor Agent

5. Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

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