Palladium-Catalyzed C–O Cross-Coupling as a Replacement for a Mitsunobu Reaction in the Development of an Androgen Receptor Antagonist

Author:

Hager Anastasia1ORCID,Guimond Nicolas1,Grunenberg Lars1ORCID,Hanisch Christine1,Steiger Sebastian1,Preuss André1

Affiliation:

1. Chemical and Pharmaceutical Development Department, Bayer AG Pharmaceuticals, Friedrich-Ebert-Str. 217-333, 42096 Wuppertal, Germany

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference21 articles.

1. Obesity and Weight Loss in Polycystic Ovary Syndrome

2. A systematic review of commonly used medical treatments for hirsutism in women

3. Heritability of Polycystic Ovary Syndrome in a Dutch Twin-Family Study

4. Nguyen, D.; Künzer, H.; Faus Gimenez, H.; Bader, B.; Köhr, S.; Fritsch, M. N-[4-(Quinolin-4-yloxy)cyclohexyl(methyl)](hetero)arylcarboxamides as androgen receptor antagonists, production and use thereof as medicinal products. Patent WO 2014001247 A1, 2014.

5. The Mitsunobu reaction in the 21st century

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