Precise Preparation of a High-Purity Key Intermediate of Tazobactam
Author:
Affiliation:
1. Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang 110016, P. R. China
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00407
Reference38 articles.
1. Chemical Modification of Tazobactam. Synthesis of 2.BETA.-((4-Substituted)-1,2,3-triazol-1-yl)methyl Penicillanic Acid Sulfone Derivatives.
2. The effect of tazobactam on the pharmacokinetics and the antibacterial activity of piperacillin in dogs
3. Rational Design of a β-Lactamase Inhibitor Achieved via Stabilization of the trans-Enamine Intermediate: 1.28 Å Crystal Structure of wt SHV-1 Complex with a Penam Sulfone
4. beta-Lactamases in laboratory and clinical resistance
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