Monitoring Continuous Crystallization of Paracetamol in the Presence of an Additive Using an Integrated PAT Array and Multivariate Methods-Reference-Cited by-同舟云学术

Monitoring Continuous Crystallization of Paracetamol in the Presence of an Additive Using an Integrated PAT Array and Multivariate Methods

Published:2016-02-25 Issue:3 Volume:20 Page:626-636
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Powell Keddon A.¹,Saleemi Ali N.²,Rielly Chris D.¹,Nagy Zoltan K.¹³

Affiliation:

1. EPSRC Centre for Innovative Manufacturing in Continuous Manufacturing and Crystallization at the Department of Chemical Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU, U.K.

2. GSK, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, U.K.

3. School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47907, United States

Funder

Engineering and Physical Sciences Research Council

European Research Council

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.5b00373

Reference64 articles.

1. Use of focused beam reflectance measurement (FBRM) and process video imaging (PVI) in a modified mixed suspension mixed product removal (MSMPR) cooling crystallizer

2. Continuous crystallization of adipic acid with ultrasound

3. Characterization of the anti-solvent batch, plug flow and MSMPR crystallization of benzoic acid

4. Near infrared and Raman spectroscopy for the in-process monitoring of pharmaceutical production processes

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