1. Drug Substance Development, GSK Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, U.K.
2. Department of Chemistry, University of Bath, Claverton Down, Bath BA2 7AY U.K.
3. Chemical Process Development, Bristol Myers Squibb,
One Squibb Drive, New Brunswick, New Jersey 08903, United States