Synthesis of Rovafovir Etalafenamide (Part III): Evolution of the Synthetic Process to the Phosphonamidate Fragment

Author:

Ambrosi Andrea1ORCID,Bringley Dustin A.1,Calimsiz Selcuk2,Garber Jeffrey A. O.2,Huynh Huy2,Mohan Sankar2,Sarma Keshab1,Shen Jinyu2,Curl Jonah2,Kwong Bernard2,Lapina Olga1,Leung Edmund2,Lin Lennie2,Martins Andrew2,McGinitie Teague3,Phull Jaspal2,Roberts Ben1,Rosario Mary2,Shi Bing1,Standley Eric A.1,Wang Li2,Wang Xueqing2,Yu Guojun2

Affiliation:

1. Process Chemistry, Gilead Sciences Inc., 333 Lakeside Drive, Foster City, California 94404, United States

2. Process Development, Gilead Alberta ULC, 1021 Hayter Road NW, Edmonton, Alberta T6S 1A1, Canada

3. Analytical Chemistry, Gilead Alberta ULC, 1021 Hayter Road NW, Edmonton, Alberta T6S 1A1, Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

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