Development of an SNAr Reaction: A Practical and Scalable Strategy To Sequester and Remove HF-Reference-Cited by-同舟云学术

Development of an SNAr Reaction: A Practical and Scalable Strategy To Sequester and Remove HF

Published:2018-08-31 Issue:9 Volume:22 Page:1086-1091
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Blacker A. John¹^ORCID,Moran-Malagon Gabriel¹,Powell Lyn²,Reynolds William¹,Stones Rebecca¹,Chapman Michael R.¹

Affiliation:

1. Institute of Process Research and Development, School of Chemistry and School of Chemical and Process Engineering, University of Leeds, Leeds LS2 9JT, United Kingdom

2. Chemical Development, AstraZeneca, Macclesfield SK10 2NA, United Kingdom

Funder

AstraZeneca

Engineering and Physical Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.8b00090

Reference30 articles.

1. Stereoselective Synthesis of Polysubstituted Piperazines and Oxopiperazines. Useful Building Blocks in Medicinal Chemistry

2. Characteristic Physical Properties and Structural Fragments of Marketed Oral Drugs

3. Kepner-Tregoe Decision Analysis as a Tool To Aid Route Selection. Part 3. Application to a Back-Up Series of Compounds in the PDK Project

4. AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

5. Synthesis and antibacterial activity of levofloxacin derivatives with certain bulky residues on piperazine ring

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Evolution of a Green and Sustainable Manufacturing Process for Belzutifan: Part 6─Development of a Nucleophilic Aromatic Substitution in Water;Organic Process Research & Development;2024-02-05

2. Atroposelective Total Synthesis of Cihunamide B;Journal of the American Chemical Society;2024-01-19

3. Al₂O₃ promoted mechanochemical nucleophilic aromatic substitution;RSC Mechanochemistry;2024

4. Palladium-catalyzed enantioselective three-component synthesis of α-arylglycine derivatives from glyoxylic acid, sulfonamides and aryltrifluoroborates;Beilstein Journal of Organic Chemistry;2023-05-25

5. Copper-Catalyzed Racemization-Recycle of a Quaternary Center and Optimization Using a Combined Kinetics-DoE/MLR Modeling Approach;The Journal of Organic Chemistry;2023-04-17