Process Research and Scale-Up Synthesis of 3-(4-Isobutyl-2-methylphenyl)propanal, a Safe and Uniquely Performing Perfumery Ingredient-Reference-Cited by-同舟云学术

Process Research and Scale-Up Synthesis of 3-(4-Isobutyl-2-methylphenyl)propanal, a Safe and Uniquely Performing Perfumery Ingredient

Published:2020-11-24 Issue:12 Volume:24 Page:2906-2914
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Lovchik Martin A.¹^ORCID,Tse Chi-Lam¹,Ellwood Simon¹

Affiliation:

1. Fragrance S&T, Givaudan Schweiz AG, Kemptpark 50, 8310 Kemptthal, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00421

Reference25 articles.

1. p-Alkyl-Benzoyl-CoA Conjugates as Relevant Metabolites of Aromatic Aldehydes With Rat Testicular Toxicity—Studies Leading to the Design of a Safer New Fragrance Chemical

2. Goeke, A.; Kraft, P.; Laue, H.; Zou, Y.; Voirol, F. Aryl-substituted alkanal compounds useful as perfume ingredients in personal and household care products. WO Patent WO2014180952A12014.

3. Synthesis of 1,3,4,5-Tetrahydro-2-benzoxepin Derivatives as Conformationally Restricted Analogues of cyclamenaldehyde-type compounds and as intermediates for highly odour-active homologues

4. Chi-Lam, T.; Lovchik, M. A.; Ellwood, S.; Goeke, A. Process of preparing 3-(4-isobutyl-2-methylphenyl)propanal. WO Patent WO2016075257A12016.

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