Solvent Switching in Continuous Multistep Chemoenzymatic Synthesis: Telescoping Enzymatic Synthesis of Chiral, Pyridine-Containing Amines with Cross-Coupling as a Case Study-Reference-Cited by-同舟云学术

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Solvent Switching in Continuous Multistep Chemoenzymatic Synthesis: Telescoping Enzymatic Synthesis of Chiral, Pyridine-Containing Amines with Cross-Coupling as a Case Study

Published:2024-05-21 Issue:7 Volume:28 Page:2683-2691
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Díaz-Kruik Pablo¹^ORCID,Roura Padrosa David²,Hegarty Eimear¹,Lehmann Hansjoerg³^ORCID,Snajdrova Radka³^ORCID,Paradisi Francesca¹^ORCID

Affiliation:

1. Department of Chemistry, Biochemistry and Pharmaceutical Sciences, University of Bern, Freiestrasse 3, 3012 Bern, Switzerland

2. inSEIT AG, Geselleschaftsstrasse 42, 3012 Bern, Switzerland

3. Biomedical Research, Global Discovery Chemistry,Novartis Pharma AG, 4056 Basel, Switzerland

Funder

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00080

Reference41 articles.

1. Nitration Chemistry in Continuous Flow using Fuming Nitric Acid in a Commercially Available Flow Reactor

2. Revisiting aromatic diazotization and aryl diazonium salts in continuous flow: highlighted research during 2001–2021

3. Design of an in vitro biocatalytic cascade for the manufacture of islatravir

4. Synthesis of Sitagliptin Intermediate by a Multi-Enzymatic Cascade System Using Lipase and Transaminase With Benzylamine as an Amino Donor

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