Unravelling the Impact of Process Impurities on the Crystallization of Ritlecitinib Tosylate Using Molecular Dynamics-Reference-Cited by-同舟云学术

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Unravelling the Impact of Process Impurities on the Crystallization of Ritlecitinib Tosylate Using Molecular Dynamics

Published:2024-09-09 Issue: Volume: Page:
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Chum Clarence KeiKwan¹,Gladwell Iain Robert²,Marziano Ivan³^ORCID,Salvalaglio Matteo⁴^ORCID

Affiliation:

1. Philip Morris International, Neuchâtel 2000, Switzerland

2. Pfizer Pharmaceutical Research & Development, Sandwich CT13 9ND, U.K.

3. Particology Ltd., Sandwich CT13 9ND, U.K.

4. Thomas Young Centre and Department of Chemical Engineering, University College London, London WC1E 7JE, U.K.

Funder

Pfizer UK

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00106

Reference32 articles.

1. Monitoring of Batch Industrial Crystallization with Growth, Nucleation, and Agglomeration. Part 1: Modeling with Method of Characteristics

2. Influence of Impurities on the Solubility, Nucleation, Crystallization, and Compressibility of Paracetamol

3. The Influence of Impurities and Additives on Crystallization

4. A bad (crystal) habit—and how it was overcome

5. A Structured Approach To Cope with Impurities during Industrial Crystallization Development

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