Increasing the Purity of Lafutidine Using a “Suicide Substrate”
Author:
Affiliation:
1. Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang 110016, P. R. China
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.8b00070
Reference19 articles.
1. Protective effect of lafutidine, a novel histamine H2-receptor antagonist, on acid reflux esophagitis in rats through capsaicin-sensitive afferent neurons
2. Protective Effect of Lafutidine, a Novel Histamine H2-Receptor Antagonist, on Dextran Sulfate Sodium-Induced Colonic Inflammation Through Capsaicin-Sensitive Afferent Neurons in Rats
3. bHirakawa, N.; Hosoda, A.; Isowa, Y.; Kashiwaba, N.; Matsumoto, H.; Nishikawa, M.; Sekine, A.; Sekine, Y.; Yamura, T. Intermediates for pyridyloxy compounds having utility as anti-peptic ulcer agents. U.S., Patent 4,977,267, 1990.
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