Process Development and Protein Engineering Enhanced Nitroreductase-Catalyzed Reduction of 2-Methyl-5-nitro-pyridine-Reference-Cited by-同舟云学术

Process Development and Protein Engineering Enhanced Nitroreductase-Catalyzed Reduction of 2-Methyl-5-nitro-pyridine

Published:2020-12-10 Issue:3 Volume:25 Page:648-653
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Bornadel Amin¹^ORCID,Bisagni Serena¹,Pushpanath Ahir¹,Slabu Iustina¹^ORCID,LePaih Jacques¹,Cherney Alan H.²^ORCID,Mennen Steven M.²^ORCID,Hedley Simon J.²,Tedrow Jason³^ORCID,Dominguez Beatriz¹

Affiliation:

1. Johnson Matthey Plc., 28 Cambridge Science Park, Milton Road, Cambridge CB4 0FP, U.K.

2. Amgen, Inc., MS 29-1-A, One Amgen Center Drive, Thousand Oaks 91320-1799, California, United States

3. Department of Drug Substance Technologies, Amgen Inc., Cambridge, Massachusetts 02142, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.0c00464

Reference27 articles.

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2. Recent Developments in the Reduction of Aromatic and Aliphatic Nitro Compounds to Amines

3. Advancement in methodologies for reduction of nitroarenes

4. Accelerated Process Development of Pharmaceuticals: Selective Catalytic Hydrogenations of Nitro Compounds Containing Other Functionalities

5. The Development of a Scalable, Chemoselective Nitro Reduction

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