The Development of a Manufacturing Route to an MCHr1 Antagonist-Reference-Cited by-同舟云学术

The Development of a Manufacturing Route to an MCHr1 Antagonist

Published:2016-03-08 Issue:3 Volume:20 Page:675-682
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Golden Michael¹,Legg Danny¹,Milne David¹,Bharadwaj M. Arun²,Deepthi K.²,Gopal Madan²,Dokka Nagaraju²,Nambiar Sudhir²,Ramachandra Puranik²,Santhosh U.²,Sharma Parhalad²,Sridharan R.²,Sulur Manjunatha²,Linderberg Mats³,Nilsson Anders³,Sohlberg Roger³,Kremers John⁴,Oliver Samuel⁴,Patra Debasis⁵

Affiliation:

1. Pharmaceutical Development, AstraZeneca, Silk Road Business Park, Macclesfield, U.K.

2. Pharmaceutical Development, AstraZeneca India, Hebbal, Bellary Road, Bangalore, India

3. Process R&D, AstraZeneca, S 151 85 Södertälje, Sweden

4. Process R&D, Albany Molecular Research (U.K.) Ltd., Mostyn Road, Holywell, Flintshire CH8 9DN, U.K.

5. Process R&D, Albany Molecular Research, Inc., 26 Corporate Circle, P.O. Box 15098, Albany, New York 12203, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.6b00006

Reference9 articles.

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2. Anti-obesity effects of small molecule melanin-concentrating hormone receptor1 (MCHR1) antagonists

3. aCasaubon, R. L.; Narayan, R.; Oalmann, C.; Vu, C. B.PCT Int. Appl., 2013059587, Apr 25, 2013.

4. bBurns, C. J.PCT Int. Appl. 2014000032, Jan 3, 2014, (Phenyl amino pyrimidine bicyclic compounds and uses thereof).

5. Spirocyclic Oxetanes: Synthesis and Properties

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