Process Development of an Efficient and Cost-Effective Telescoping Route to a Key Synthetic Precursor for the Preparation of a Renin Inhibitor-Reference-Cited by-同舟云学术

Process Development of an Efficient and Cost-Effective Telescoping Route to a Key Synthetic Precursor for the Preparation of a Renin Inhibitor

Published:2019-02-19 Issue:4 Volume:23 Page:499-511
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Nonoyama Akihito¹^ORCID,Nakai Yoshio²,Lee Shoukou²,Suzuki Satoshi³,Ando Takeya¹,Fukuda Nobuhisa²,Tanaka Hiroaki¹,Takahashi Kazuhiko⁴

Affiliation:

1. Process Chemistry Research and Development Laboratories, Sumitomo Dainippon Pharma Co., Ltd., 1-98 Kasugade-naka 3-chome, Konohana-ku, Osaka 554-0022, Japan

2. Chemistry Research Unit Drug Research Division, Sumitomo Dainippon Pharma Co., Ltd., 1-98 Kasugade-naka 3-chome, Konohana-ku, Osaka 554-0022, Japan

3. Formulation Research and Development Laboratories, Sumitomo Dainippon Pharma Co., Ltd., 13-1, Kyobashi 1-chome, Chuo-ku, Tokyo 104-8356, Japan

4. Technology Research and Development Division, Sumitomo Dainippon Pharma Co., Ltd., 33-94, Enoki-cho, Suita, Osaka 564-0053, Japan

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.8b00414

Reference56 articles.

1. Development of Inhibitors of the Aspartyl Protease Renin for the Treatment of Hypertension

2. Unmet Needs in Managing Hypertension: Potential Role of Direct Renin Inhibition

3. Direct Renin Inhibition

4. Prodrugs and targeted drug delivery

5. Prodrug strategies to overcome poor water solubility

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Applications of palladium-catalyzed C–N cross-coupling reactions in pharmaceutical compounds;RSC Advances;2023

2. Recent Applications of Pd-Catalyzed Suzuki–Miyaura and Buchwald–Hartwig Couplings in Pharmaceutical Process Chemistry;Organics;2022-01-18