Scalable Process for Making 5,7-Dichlorotetrahydroisoquinoline-6-carboxylic Acid Using Methylene as the Protecting Group-Reference-Cited by-同舟云学术

Scalable Process for Making 5,7-Dichlorotetrahydroisoquinoline-6-carboxylic Acid Using Methylene as the Protecting Group

Published:2021-10-19 Issue:11 Volume:25 Page:2447-2452
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Xu Wanbin¹²,Gong Xudong³,Odilov Abdullajon¹²,Hu Tianwen²,Jiang Xiangrui¹^ORCID,Zhu Fuqiang³,Guo Shuang³,Jiang Dehui³,Wu Mingjun³,Shen Jingshan¹²^ORCID

Affiliation:

1. CAS Key Laboratory for Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, People’s Republic of China

2. University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing 100049, People’s Republic of China

3. Topharman Shanghai Co., Ltd., Building 1, 388 Jialilue Road, Zhangjiang Hitech Park, Shanghai 201203, People’s Republic of China

Funder

Science and Technology Commission of Shanghai Municipality

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00229

Reference35 articles.

1. Lifitegrast: a novel drug for patients with dry eye disease