Development of a Novel Process for the Kilogram-Scale Synthesis of Spiro[1H-pyrido[2,3-d][1,3]oxazine-4,4′-piperidine]-2-one-Reference-Cited by-同舟云学术

Development of a Novel Process for the Kilogram-Scale Synthesis of Spiro[1H-pyrido[2,3-d][1,3]oxazine-4,4′-piperidine]-2-one

Published:2018-07-26 Issue:9 Volume:22 Page:1236-1240
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Mowrey Dale R.¹,Reif James J.¹,Milkiewicz Karen L.¹,Allwein Shawn P.¹^ORCID

Affiliation:

1. Teva Pharmaceuticals, 383 Phoenixville Pike, Malvern, Pennsylvania 19355, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.8b00202

Reference28 articles.

1. aChristopher, J. A.; Congreve, M. S.; Bucknell, S. J.; Deflorian, F.; Pickworth, M.; Mason, J. S. Preparation of pyridinyl piperidinyl piperazines as CGRP receptor antagonists. PCT Int. Appl. WO 2017072721, 2017.

2. bChristopher, J. A.; Congreve, M. S.; Bucknell, S. J.; Deflorian, F.; Pickworth, M.; Mason, J. S. Preparation of diazospirodecyl piperidinyl indazoles as CGRP receptor antagonists. PCT Int. Appl. WO 2017072722 A1, May 4, 2017.

3. cSelnick, H. G.; Bell, I. M. Imidazobenzazepine cgrp receptor antagonists. US 8796260 B2, Aug 5, 2014.

4. dWilliams, T. M. Heterocyclic benzodiazepine cgrp receptor antagonists. US 7947678 B2, May 24, 2011.

5. eFournier, J.F.; Clary, L.; Thoreau, E. Preparation of heterocyclic compounds as GCRP receptor antagonists and their use in medicine and in cosmetics. PCT Int. Appl. WO 2016102882 A1, June 30, 2016.

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