Route Optimization and Manufacture of Multihundred Grams of a Ghrelin Receptor Agonist-Reference-Cited by-同舟云学术

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Route Optimization and Manufacture of Multihundred Grams of a Ghrelin Receptor Agonist

Published:2018-09-05 Issue:9 Volume:22 Page:1174-1187
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Karlsson Staffan¹^ORCID,Gardelli Cristina²^ORCID,Lindhagen Marika¹,Nikitidis Grigorios¹,Svensson Tor²

Affiliation:

1. Early Chemical Development, Pharmaceutical Sciences, IMED Biotech Unit, AstraZeneca Gothenburg, SE-431 83 Mölndal, Sweden

2. Medicinal Chemistry, Respiratory, Inflammation and Autoimmunity, IMED Biotech Unit, AstraZeneca Gothenburg, SE-431 83 Mölndal, Sweden

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.8b00179

Reference30 articles.

1. The hunger hormone ghrelin in cachexia

3. Treatment of Cachexia With Ghrelin in Patients With COPD

4. Enzyme-catalyzed asymmetric synthesis. 8. Enantioselectivity of pig liver esterase catalyzed hydrolyses of 4-substituted meso cyclopentane 1,2-diesters

5. α,β-Cyclic-β-benzamido hydroxamic acids: Novel templates for the design, synthesis, and evaluation of selective inhibitors of TNF-α converting enzyme (TACE)

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