Manufacturing Development and Genotoxic Impurity Control Strategy of the Hedgehog Pathway Inhibitor Vismodegib-Reference-Cited by-同舟云学术

Manufacturing Development and Genotoxic Impurity Control Strategy of the Hedgehog Pathway Inhibitor Vismodegib

Published:2016-08-11 Issue:8 Volume:20 Page:1509-1519
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Angelaud Remy,Reynolds Mark,Venkatramani Cadapakam,Savage Scott,Trafelet Huldreich¹,Landmesser Thomas¹,Demel Peter¹,Levis Michael¹,Ruha Olivier¹,Rueckert Baerbel¹,Jaeggi Heinz¹

Affiliation:

1. Siegfried AG, Untere Brühlstrasse 4, CH-4800 Zofingen, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.6b00208

Reference22 articles.

1. Targeting the Hedgehog pathway in cancer

2. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

3. Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome

4. Human Homolog of patched , a Candidate Gene for the Basal Cell Nevus Syndrome

5. Gunzner, J. L.; Sutherlin, D. P.; Stanley, M. S.; Bao, L.; Castanedo, G.; Lalonde, R. L.; Wang, S.; Reynolds, M. E.; Savage, S. J.; Malesky, K.; Dina, M. S.WO2009126863, 2009.

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis of Pharmaceutically Relevant Arylamines Enabled by a Nitroreductase from Bacillus tequilensis;ChemBioChem;2024-04-19

2. An alternative method for the preparation of vismodegib: A tool for an undergraduate laboratory course;Journal of Chemical Research;2023-11

3. Synthesis of Vismodegib Derivatives as Potential Smo Agonist: A Case of Undergraduate Experimental Teaching;Russian Journal of General Chemistry;2023-10

4. Development of a Control Strategy for Hydrogenation of Aryl Nitro Analogs by Kinetic Justification;Organic Process Research & Development;2023-09-05

5. Pyridine ring as an important scaffold in anticancer drugs;Recent Developments in the Synthesis and Applications of Pyridines;2023