Building a Quaternary Stereogenic Center on Dihydroazaindole Carboxylic Acid through Scalable Process Development-Reference-Cited by-同舟云学术

Building a Quaternary Stereogenic Center on Dihydroazaindole Carboxylic Acid through Scalable Process Development

Published:2023-10-09 Issue:11 Volume:27 Page:2045-2056
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Lee Jaehee¹^ORCID,Li Guisheng¹,Zeng Xingzhong¹,Haddad Nizar¹^ORCID,Abeyta Vincent²,Pennino Scott²,Wu Lifen¹,Gao Joe²,Jiang Qi²,Lorenz Jon C.¹,Wang Jun¹,Wu Jiang-Ping¹^ORCID,Brazzillo Jason¹,Sarvestani Max¹,Wang Xiao-Jun¹^ORCID,El-Awa Ahmad¹,Leung Joyce C.¹^ORCID,Qu Bo¹^ORCID,Tan Zhulin¹^ORCID,Song Jinhua J.¹

Affiliation:

1. Chemical Development US, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut 06877, United States

2. Material and Analytical Sciences, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut 06877, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00231

Reference23 articles.

1. Copper Catalyzed Regioselective and Stereospecific Aziridine Opening with Pyridyl Grignard Nucleophiles

2. Molecular Recognition of Protein Kinase Binding Pockets for Design of Potent and Selective Kinase Inhibitors

3. Novel preparation of functionalized iodotetrahydronaphthyridine, iodoazaindoline, and iodotetrahydropyridoazepine systems

4. Diastereo- and Enantioselective CuH-Catalyzed Hydroamination of Strained Trisubstituted Alkenes

5. Versatile Homoallylic Boronates by Chemo‐, S N 2′‐, Diastereo‐ and Enantioselective Catalytic Sequence of Cu−H Addition to Vinyl‐B(pin)/Allylic Substitution